Primary sclerosing cholangitis: One disease or several?
نویسندگان
چکیده
منابع مشابه
Primary Sclerosing Cholangitis: Palliative Surgery or Transplantation?
The natural history of primary sclerosing cholangitis (PSC) is poorly defined and its management remains controversial. Forty-eight symptomatic patients (median age 39 years, range 8-67 years; 30 male) with PSC were reviewed retrospectively. Thirty patients had infllammatory bowel disease. Four patients (8 per cent) developed or had an associated malignancy. Twenty-one (44 per cent) died; overa...
متن کاملPrimary sclerosing cholangitis as an intractable disease.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown origin which eventually results in liver cirrhosis. The disease is reported to be more common among the Western population than in the Asian population. Asian experience remains limited. Diagnosis and treatment standards in the Far East have largely followed those in the West, including liver transplantation....
متن کاملInflammatory Bowel Disease and Primary Sclerosing Cholangitis
Inflammatory bowel disease (IBD) is a chronic condition which is characterized by recurrent immune-mediated inflammation of the gastrointestinal system. IBD is frequently associated with extraintestinal manifestations (EIM) characterized by involvement of multiple organs. EIM occur in 21% to 47% of IBD patients (Navaneethan & Shen, 2010). While some extraintestinal manifestations are encountere...
متن کاملPrimary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disorder of the biliary system that results in progressive fibrosis and strictures of the intrahepatic and extrahepatic bile ducts. Typical radiological changes on retrograde cholangiography are shown in Figure 1. These strictures cause cholestatic liver disease that may progress to end-stage cirrhosis. The disorder has a strong ass...
متن کاملPrimary Sclerosing Cholangitis: Introduction
The prevalence of primary sclerosing cholangitis in the United States is approximately 1–6 cases per 100,000 population. Most patients with primary sclerosing cholangitis are men (75%) with an average age of approximately 40 years at diagnosis. The overwhelming majority of patients affected with primary sclerosing cholangitis are Caucasian. The etiology is unknown but current opinion favors an ...
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ژورنال
عنوان ژورنال: Clinical Liver Disease
سال: 2014
ISSN: 2046-2484,2046-2484
DOI: 10.1002/cld.318